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While highly effective for glycemic control and weight reduction, gastrointestinal adverse effects are commonly reported, with constipation rates varying by indication and dosageapproximately 3-9% in diabetes treatment (Ozempic, Rybelsus) and up to 24% in weight management (Wegovy)

The study highlights the potential benefits of semaglutide in long-term diabetes management, emphasizing the importance of a holistic approach that combines medication with lifestyle changes

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