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It is an anti-ulcer peptide (9-12), interacting with NO-system (13), and, unlike other peptides, it is particularly stable in gastric juice (14) and is used consistently without a carrier (9-11, 13-24), being safe in patients with the inflammatory bowel disease (coded PL-10, PLD 116, PL 14736) (21)

As a supplement, creatine has been widely investigated

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T2DM patients have much higher SGLT2 expression in their kidneys than do healthy individuals

ROS are also involved in ovulation, follicular rupture and corpus luteum formation

Many of these associations occur within the spectrum of autoimmune polyendocrine syndromes (APS)