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Researchers who study the pancreatic peptide hormone system will recognize glucagon as the metabolic counterweight to insulin, and harnessing it pharmacologically opens therapeutic possibilities that the research community has pursued for decades

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Currently approved weight management pharmacotherapy in the UK includes: Semaglutide (Wegovy) a GLP-1 receptor agonist approved by the MHRA for chronic weight management in adults, subject to NICE Technology Appraisal eligibility criteria [3] [5] Tirzepatide (Mounjaro) a dual GIP/GLP-1 receptor agonist approved by the MHRA for the treatment of type 2 diabetes

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