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More physiologically relevant models such as 3D organoids, patient-derived xenografts, and genetically engineered mice are needed to better predict nanoplatform behavior

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In this case, the oxidative phase of the PPP generates two molecules of NADPH and one molecule of ribose 5-phosphate

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Muntean DM, Sturza A, Dnil MD, Borza C, Duicu OM, Morno C (2016) The role of mitochondrial reactive oxygen species in cardiovascular injury and protective strategies