Yvett Penny says: It has been 4 days since I started using the cream
For TB-500, research protocols commonly reference loading-phase doses of approximately 2-2.5mg twice weekly during the initial period, transitioning to maintenance doses of approximately 2-2.5mg once weekly or every other week
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References Abreu R.V., Silva-Oliveira E.M., Moraes M.F.D., Pereira G.S., Moraes-Santos T
However, it may have some protective effects against skin aging and may help reduce freckles and age spots to some extent (1)
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