Gallic acid improves comorbid chronic pain and depression behaviors by inhibiting P2X7 receptor-mediated ferroptosis in the spinal cord of rats
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Unstable dopamine signaling , irritability, augmentation-resistant depression or thought dysregulation where full D2 blockade may be excessive
Antioxidant glutathione (GSH) is found in high concentrations in many tissues within the human body and has been shown to play roles in mitigating oxidative stress and inflammation, maintaining redox balance, enhancing metabolic detoxification processes, and regulating immune function
Sullivan KE
At the other end of the scale, controls for four studies were poorly defined potentially biasing the results [46, 47, 89, 98]