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Acknowledgements This work was supported by grants from the Ministerio de Ciencia, Innovacin y Universidades (MCIU) Plan Estatal de I+D+I 2018, a la Agencia Estatal de Investigacin (AEI) y al Fondo Europeo de Desarrollo Regional (MCIU/AEI/FEDER, UE): RTI2018-097455-B-I00