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These include: Nausea (affecting more than 1 in 10 people) Vomiting and diarrhoea Constipation Abdominal pain or discomfort Dyspepsia (indigestion) Headache Injection site reactions (redness, itching, or bruising) Most gastrointestinal side effects tend to improve over time as the body adjusts to the medication

There's no doubt that Roche is playing catchup in the category, one of a lengthening list of pharma companies that are hoping to hit on effective 'me-too' products that can make a dent in the substantial lead held by market leaders Novo Nordisk and Eli Lilly, which already have injectable GLP-1s for diabetes and obesity on the market