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The trial included 92 participants, predominantly male, with an average age of 58 years, all of whom had a body mass index (BMI) of 27 or higher

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Its core pathological feature is excessive accumulation of adipose tissue, accompanied by abnormal proliferation, differentiation, and metabolic dysfunction of adipocytes, which in turn induce a series of complications including insulin resistance, nonalcoholic fatty liver disease, and cardiovascular diseases

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