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NC = Less than 10% change in plasma concentration

Researchers exploring this route typically begin with conservative doses and titrate based on observed effects

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Findings from the pivotal New England Journal of Medicine trial confirmed a 4.3% reduction in BMI over 56 weeks, supporting its clinical effectiveness in this age group

Initiating or increasing doses immediately prior to or during Ramadan is advised against due to potential side effects

metabolomic results illustrate an expression of bacterial genes, rather than human (194)