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We detected a lower arginine/proline media ratio (lower metabolite concentrations in arginine medium compared to proline medium) for 2-oxoglutarate, linoleate, 11,14-eicosadienote, proline, 2-aminoadipate, pyroglutamate, para-toluate, 2-aminobutyrate, lysine, glutamine, alanine, glutamate, serine, and margarate in gdh3 / gdh3 mutants compared to wild-type