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Bemeur C, Desjardins P, Butterworth RF

When targeting the delicate skin around the eyes, lighter-weight eye serums with less potent concentrations might provide more suitable care

UA treatment (16 mg/kg, intravenously) immediately after transient ischemia results in a consistent reduction in brain damage and neurological impairment [148]

Often, this is true

For instance, in M1 pro-inflammatory macrophages (Ms), there is a metabolic break at isocitrate dehydrogenase in the TCA cycle due to suppression of its mRNA expression, leading to the accumulation of citrate and itaconate, which drive lipid synthesis and stabilization of anti-inflammatory transcription factors, such as nuclear factor-erythroid factor 2-related factor 2 (NRF2) and activating transcription factor 3 (15)

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