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The upregulated gene clusters are enriched in extracellular matrix components (collagens I and III, decorin, elastin), antioxidant defense systems (superoxide dismutase, glutathione-related enzymes), DNA repair pathways, and anti-inflammatory mediators including IL-10 and TGF-beta family members

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10.1016/j.freeradbiomed.2022.06.232 19 FlohL.ToppoS.OrianL

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Funding The research was supported in part by Grants-in-Aid for Challenging Exploratory Research and Scientific Research (B) from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Numbers JP26660218, JP21H02347, and JP24K01911, respectively) and by grant funds from the Uehara Memorial Foundation and Ito Foundation (all to R