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The mechanistic rationale is strong, the safety profile is established, and the observation that psoriatic arthritis patients have lower thymosin alpha-1 levels is suggestive

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J Hum Genet 53(11):10121015 Trinh J, Zeldenrust FM, Huang J, Kasten M, Schaake S, Petkovic S, Madoev H, Grnewald A, Almuammar S, Knig IR (2018) Genotype-phenotype relations for the Parkinsons disease genes SNCA, LRRK2, VPS35: MDSGene systematic review