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34 The results of HDL-C in our animal model of T2DM combined with NALFD do not match the results of previous clinical studies, probably because animal model cannot completely mirror human illness

Tirzepatide may be considered when semaglutide is not tolerated, although renal benefits remain to be confirmed in dedicated trials (TREASURE-CKD, ClinicalTrials.gov ID NCT05536804)

Full indications and limitations appear in the FDA Prescribing Information

An area of interest for GLP-1 agents is their potential use in treating polycystic ovarian syndrome (PCOS)

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