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Mid-life, higher levels of UA were associated with faster cognitive decline even after further adjustment (25-year global z-score difference, 0.149

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There is one open-label intravenous safety pilot in two healthy adults, who received single doses of 10 mg and 20 mg with no comparator, no blinding, and short-term observation limited to vital signs, self reported symptoms and labs across two days [4]

Blood glutathione redox status and global methylation of peripheral blood mononuclear cell DNA in Bangladeshi adults

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Normally, these cytokines are used to trigger an inflammatory response against infection (such as a fever)