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Other participants in the TCA cycle are also more active in KRAS-mutant tumors, particularly in pancreatic ductal adenocarcinoma (PDAC), where the increased expression of GOT1/2 supports glutamine metabolism while producing NADPH to maintain REDOX balance [50]

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The intrathecal administration of HGF also exerts positive functional recovery and protection of myelinated areas in animal models of SCI (Kitamura et al., 2011)