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Introduction Glutathione is a powerful antioxidant composed of three amino acids: cysteine, glutamate, and glycine

For example, an acetylation defect is observed in mutant p53 3 KR , which indirectly inhibits cysteine absorption and reduces GSH consumption, leading to lipid peroxidation and ferroptosis (Jiang et al., 2015)

Drug-induced GR inhibition : Several medications, including antimalarials, antipsychotics, and certain chemotherapeutic agents, can inhibit GR activity

Proc Natl Acad Sci USA 93:1450314508 Semsey S, Virnik K, Adhya S (2005) A gamut of loops: meandering DNA

Costaguta, G., Duncan, M