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The latest research and trials on the effect of GLP-1RAs in the eye were searched until April 2025, including thorough cellular studies, animal studies, and clinical observation surrounding glaucoma, diabetic retinopathy, and other ocular diseases

Accessed April 16, 2024 .] GLP-1s Past, Present and Future Given the recent craze, it may surprise some that the GLP-1 drug Saxenda ( liraglutide ) was approved by the FDA for weight reduction in people without T2D 10 years ago

It is not licensed by the MHRA and remains in Phase 3 clinical trials, with one programme expected to conclude in May 2026 [5][6]

If and when approvals happen, NHS access would follow a separate NICE appraisal

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