glp 1 and gip function GLP‐1, the two incretin hormones: Similarities and differences Mechanisms underlying GLP-1, GIP, and

PYY(3-36) predominantly acts through the Y2 receptor (Y2R) in the hypothalamus to suppress appetite and in peripheral tissues (adipose, skeletal muscle, liver) to enhance insulin sensitivity

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These receptors are in the digestive system and brain, so targeting them can change our hormone balance, helping to increase satiety after a meal and reduce the speed at which nutrients move through the digestive tract

The appetite-suppressing effect of GLP-1 is mediated by its action in the brain, whereas its glucose-lowering effect is mainly attributed to enhancement of glucose-stimulated insulin secretion [74]

Ozempic also causes muscle loss

(The following appear in both Metabolic Daily and Glucose Control