Successful hydrophobication of GSH-AuNCs and their excellent colloidal stability in organic solvents encouraged us to evaluate their encapsulation into PLGA nanoparticles using a modified nanoprecipitation method and the emulsion-evaporation method, as detailed earlier in the manuscript
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Short-term clinical trials have sometimes reported minimal or no significant shifts in gut microbiota despite marked metabolic improvements
Additionally, their associated benefits of reduced blood glucose content (glycemia), kidney disease, fatty liver, and improved cardiovascular functioning make them a viable alternative to conventional bariatric surgery and underscore significant medical advances in combatting obesity
The mechanism by which metformin acts by regulating the gut microbiota needs to be further clarified
[15] Akiska, Y.M., Vidal, S.I., Menta, N