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PMID: 37477848

For redox metabolism we investigated total (tGSH) and free (fGSH) reduced glutathione, oxidized glutathione (GSSG), the total and free glutathione redox ratios, total cysteine, glutamyl-cysteine and cysteinyl-glycine

The large heterogeneity for some outcomes, such as CAD, may suggest different mechanisms underlying the genetic associations or the existence of pleiotropy [37]

Its use for general fat loss is considered off-label

The Shank3-mutant mouse model is one of the most commonly used models to study epigenetic enzymes, and it was found that using histone methyltransferase inhibitors and histone acetylase inhibitors alone 520,521,522 or in combination 523 can both significantly improve NMDA dysfunction and social interactions in Shank3-mutant mice

All subjects were informed on phone to fast on the assessment day