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Biologic activity of mitochondrial metabolites on aging and age-related hearing loss

Evans M, Guthrie N, Pezzullo J, Sanli T, Fielding RA, Bellamine A

doi: 10.1038/s41590-021-00993-3 68 WangTZhangZDengZZengWGaoYHeiZet al

Achieving breakthroughs in MASH therapeutics remains a formidable challenge

Targeting Ferroptosis as a Promising Therapeutic Strategy for Ischemia-Reperfusion Injury

Adverse effects included higher risks of nausea, vomiting and diarrhea, while risks of suicide, hypoglycemia, retinopathy, and pancreatitis were not increased