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Maquart and colleagues reported stimulation of collagen synthesis in fibroblast cultures by GHK-Cu, while later work connected GHK-Cu to matrix remodeling enzymes and inhibitors [4], [5]

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Cost comparison for ongoing treatment: Brand-name Wegovy cash-pay: $349 per month Compounded semaglutide: $199 per month Monthly savings with compounded: $150 Over 12 months of treatment: Brand-name Wegovy: $4,188 (assuming $199 for 2 months + $349 for 10 months) Compounded semaglutide: $2,388 Annual savings: $1,800 The savings with compounded semaglutide are less dramatic than before Novo Nordisks price reduction but still meaningful over extended treatment periods