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Each mouse was gently placed in the center of a clear acrylic open-field arena (40 40 40 cm)

Gamma-H2AX, generated from the rapid phosphorylation of H2AX histone protein at the serine-139 position in early response to a broad range of DNA lesions, is a highly effective biomarker for DNA strand breaks and DNA oxidation and plays a central role in sensing and repairing DNA damage [52,53,54]

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Tomita H, Tanaka K, Tanaka T, Hara A

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Proabsorptive action of gum Arabic in isotonic solutions orally administered to rats