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In this work, we innovatively employed a ligand-mediated confined polymerization strategy to co-immobilize atomically dispersed Ru-N 5 active sites and Ru atomic clusters (2.26%) on exfoliated ultrathin 2D g-C 3 N 4 (Ru SA+AC ), leveraging their superior antioxidant activity to delay the progression of OA

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This 72-hour window is a critical safety threshold