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Using a continuous glucose monitor (CGM) device with alarm function and the possibility of remote monitoring of CGM data would also help mitigate hypoglycemic events in this context. Thomas Scherer, MD, deputy chief, Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria For Scherers two patients, uptitration of tirzepatide to the maximal dose of 15 mg a week was necessary, but in addition to the weight they lost, they did achieve significant improvements in insulin resistance (which can be quite pronounced in the setting of AS) as well as reduced hyperphagia
DOI: 10.1007/s12325-019-01080-8
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Cascading of all four enzymes in vivo gave a strong L-carnitine biosensor signal (combination H) indicating that the pathway operated as anticipated
