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The copper-peptide bond that makes GHK-Cu effective for tissue repair and collagen synthesis is also what makes it temperature-sensitive after mixing
The first step is rate-limiting and subject to feedback inhibition by glutathione itself, holding intracellular concentrations in the low millimolar range, typically 1 to 8 mM (Griffith, Free Radical Biology and Medicine, 1999
If you need knockout sedation Z-drugs/antihistamines (short-term, with cautions)
Proc Natl Acad Sci USA 86: 13981400
General wellness and longevity Some researchers use GHK-CU as a general longevity compound based on its broad gene expression effects favoring tissue maintenance and repair
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