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Although rare, adverse effects of high-dose vitamin B12 have been reported, including allergic reactions such as fever, rash, itching, hot flushes, dizziness, and nausea, across all cobalamin forms and administration routes (Caballero et al., 2007)

Naveed Sattar, a professor of cardiometabolic medicine at the University of Glasgow, who was not involved in this study, said in a release

JAMA 323(12):11751183

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En algunos casos, estos medicamentos no se recomiendan en presencia de estas condiciones

GLP-1RAs improve weight loss, fatty acid metabolism and insulin signalling, which may benefit cardiovascular health [36]