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The critical role of the redox-sensitive transcription factor Nrf2 is highlighted by findings that Nrf2-deficient mice exhibit increased susceptibility to prolonged, noise-induced tinnitus-like behavior, accompanied by heightened microglial activation and neuroinflammation (Yang et al., 2025)

The peptide demonstrates protective and healing effects across the entire GI tract, from esophageal to colonic tissue

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significant skin pigmentation changes require dermatological care

Encapsulation into nanoparticles To enhance the pharmacological properties of the metal complex and provide cancer selectivity, Ru(II)-OH was incorporated into a polymer backbone that could self-assemble into tumor-targeting nanoparticles