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All peptides, including fluorescein isothiocyanate (FITC)-labeled p53 TAD (42-57), were manufactured by Dandicure (Ochang, Korea) at a purity of 95%

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Melatonin can trigger apoptosis by acting on several cytosolic pathways such as the PI3K/AKT/mTOR, the p38 kinase pathway of mitogen-activated protein kinases (MAPK/ERK or MAPK pathway), and the c-Jun N-terminal pathway (JNKs) JNK/c-jun [32]