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The most common serious laboratory abnormalities (grade 3 or 4, 2%) were leukopenia, anemia, decreased phosphate, hypocalcemia, hyponatremia, increased liver enzymes, thrombocytopenia, and increased alkaline phosphatase levels (NCT03037385) [36,37]

Janus kinase3 (JAK3) is expressed in erythrocytes, phosphorylated upon energy depletion, and involved in regulating eryptosis by triggering cell membrane scrambling (Bhavsar et al., 2011)

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By helping neutralize free radicals, glutathione may also help promote healthy aging.