Home-based physiological monitoring using wearable devices and mobile apps is also becoming more widespread 46
Ionizing radiation induces DNA damage through direct and indirect pathways, with the direct pathway causing DNA damage (e.g., SSB and DSB) that leads to vascular endothelial cell injury and alveolar epithelial cell injury, apoptosis, increased cytokine secretion, and EMT/ EndMT, ultimately resulting in increased vascular permeability, pulmonary edema, pulmonary fibrosis, epithelial barrier damage, and alveolar dysfunction, while the indirect pathway involves ionization of water molecules in irradiated cells to generate reactive oxygen species (ROS) that damage DNA, activate the NF-B pathway to promote cytokine secretion and participate in the development of RP, and disrupt junction proteins to further increase vascular permeability, with these radiation-induced changes collectively driving the pathogenesis of RP and RIPF
Those differences directly affect how the product should be prescribed, stored, shipped, and used
PMCID: PMC10165082
Never assume that clear appearance means the medication is safe
Within two weeks, I noticed my range of motion improving and less next-day soreness
