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Microdosing GLP-1 involves starting with smaller doses than standard prescriptions, following a low and slow approach

However, the EMA advises against using liraglutide and semaglutide in individuals with a creatinine clearance below 30 mL/min, which corresponds to CKD stages 4 and 5 or kidney failure

78 The elimination half-life of liraglutide is 13 h, and only one injection per day is required

Pairing microdosing GLP-1 with healthy habits can improve results and support long-term success

Their clinical advantage in managing type 2 diabetes and obesity has positioned them strongly in treatment guidelines

Sridonpai P, Prachansuwan A, Praengam K, Tuntipopipat S, Kriengsinyos W