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Certain classical ASMs (e.g., phenobarbital, benzodiazepines, topiramate, vigabatrin) primarily act by broadly suppressing neuronal excitability or markedly enhancing GABA receptor activity

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The biological effects of activated 1,25(OH)D are mediated via its ligand-activated nuclear receptor, the VDR, which is broadly expressed across tissues and particularly enriched in skin cells

1 2 DEA, US Department of Justice

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