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An altered pH in the solvent can cause them to denature, aggregate, or simply fail to dissolve properly
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Supplementary material The Supplementary Material for this article can be found online at: References 1 ChenJ.WangM.JoyceA.DeFrancoD.KavosiM.XuX.et al (2014)
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11 Bone marrow suppression is common and potentially affects all cell lines, with megaloblastic anemia being most common
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