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To further investigate the relative contributions of MOR-expressing enteric versus MOR-expressing PVN Glu neurons in morphine-induced constipation, we infused AAV-DIO-shMOR-EGFP or AAV-DIO-EGFP control virus into the PVN of VgluT2-Cre mice, then induced constipation by i.p

Indeed, Sp was able to restore cytosolic and mitochondrial redox balance in neuronal cell line SHSY-5Y subjected to 1-methyl-4-phenylpyridinium (MPP + ) treatment which is known to cause mitochondria dysfunction and oxidative stress through complex I inhibition 1 (Fig

& Matsumoto, M

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The manufacturer also notified its U.S

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