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PharmacoEconomics Open 7 , 579591 (2023)

Abdominal symptoms are usually mild and resolve as the gastrointestinal system adapts to slower transit times

They can discuss temporary strategies, confirm your prescription is current, or adjust your next dosing date to minimize metabolic disruption

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Nausea Vomiting Diarrhea Abdominal pain Constipation Dyspepsia (indigestion) Decreased appetite Headache Fatigue Pancreatitis Gallbladder disease (cholelithiasis, cholecystitis) Acute kidney injury (usually from dehydration via GI fluid loss) Hypoglycemia (mainly when combined with insulin or a sulfonylurea) Diabetic retinopathy complications Increased resting heart rate Thyroid C-cell tumours (boxed warning

Peptide therapy involves using synthetic peptides to compensate for the decline in natural production