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Whereas, further rise in the ROS level is accompanied with down regulation of cellular antioxidant defense systems in tumor malignancy through various molecular targets including nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) and nuclear respiratory factor 2 (Nrf2) [6, 7]

When DEPTOR was rescued in sh-ILF3 cells, the WB results revealed that the protein levels of p-mTOR, PD-L1, SLC7A11, and GPX4 were also increased compared to those in the sh-ILF3 group (Fig

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Advancement in understanding the role of ferroptosis in rheumatoid arthritis

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