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Only the math changed

(There are several studies involving animals, but not human subjects.) What research does show is that people who are overweight tend to be low in vitamin B12

2019 Jan-.Available from: 5 Bicket MC, Horowitz JM, Benzon HT, Cohen SP

Lipodystrophy often features reduced SHBG and IGFBP-1, whereas receptoropathies show normal or elevated levels [202]

But is it actually a problem