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Chinese medicine formula Kai-Xin-San ameliorates depression-like behaviours in chronic unpredictable mild stressed mice by regulating gut microbiota-inflammation-stress system

Berberine may cause gastrointestinal side effects (diarrhea, cramping), which can overlap with GLP-1-induced nausea or appetite changes, making symptom attribution complex

A large proportion come from China, where imports of hormone and peptide compounds have increased dramatically: US customs data shows they hit $328m in the first three-quarters of 2025, up from $164m in the same period the previous year, the New York Times reported