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Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring V600EBRAF

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These findings support the idea that BPA may facilitate the progression of prostate tumours to the ADT-resistant stages, influencing the duration and magnitude of therapeutic response in PCa patients

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The assay is optimized to operate at an acidic pH of 5.0, which enhances the stability of the colored complex and minimizes interference from competing reactions