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More from SheKnows The article follows two elementary-aged twins who have obesity and are currently being treated with a GLP-1 with great success

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[DOI] [PubMed] [Google Scholar] 74.Terzyan SS, Cook PF, Heroux A, Hanigan MH: Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation

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Important safety considerations include a boxed warning for risk of thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), and risks of pancreatitis, gallbladder disease, acute kidney injury with dehydration, and diabetic retinopathy complications with semaglutide

Nausea, vomiting, diarrhea, and constipation affect up to 73% of patients during dose escalation