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They contain semaglutide, a chemical that mimics a natural hormone in the body called GLP-1 (glucagon-like peptide-1), which is released after eating

Prolonged cAMP signaling and homologous desensitization Intuitively, reduced loss of surface GLP-1R with exendin-phe1 should permit greater access to extracellular ligand during continuous exposure, with fast recycling ensuring that the receptors are maintained in a sensitized state

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