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We establish NAPstar measurements in yeast, plants and mammalian cell models, revealing a conserved robustness of cytosolic NADP redox homeostasis

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The synthesized system displayed a highly pH-responsive behavior with a half-life of 0.2, 0.4, and 0.9 h at pH 4, 5, and 6, respectively which displayed a very good stability at pH 7.4

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