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The semaglutide shortage was declared resolved, and the legal basis for mass compounding largely disappeared

Ibrahim, Hasan

More research is needed ( The Indian coleus plant (which contains forskolin) has been a part of traditional herbal medicine for centuries

The absence of dedicated clinical trials for compounded preparations reflects regulatory structure, not necessarily reduced efficacy

It is the same active ingredient as Mounjaro, but Zepbound is the brand specifically FDA-approved for chronic weight management and, more recently, for moderate-to-severe obstructive sleep apnoea in adults with obesity

Both semaglutide and tirzepatide reduce the severity of heart failure with preserved ejection fraction (65, 66)