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The calculation for pI involves averaging the pKa values associated with the second and third ionizable groups, resulting in a pI of 7.59, expressed as: pI = 1/2 (pKa2 + pKa3)

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The findings revealed significantly increased MDA levels and reduced TAC, SOD, and catalase levels in CKD patients with and without hypertension, indicating abnormal renal functions [135]