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Side Effects Comparison# Pemvidutide Side Effects# GI adverse events were consistent with the GLP-1 class in Phase 2 trials, generally well tolerated
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Patients typically report feeling satisfied with smaller portions and experiencing less frequent hunger between meals
In addition, further research is needed to clarify potential sex-specific differences and to better understand the central and peripheral mechanisms of action of GLP-1 and amylin analogues, including whether their effects are additive, synergistic, or potentially divergent in different clinical contexts
Aroda, Efficacy and Safety of Once-Weekly Semaglutide Versus Exenatide ER in Subjects With Type 2 Diabetes (SUSTAIN 3): A 56-Week, Open-Label, Randomized Clinical Trial