Resolution of Hepatic Steatosis: In patients with Metabolically Dysfunctional-Associated Steatotic Liver Disease [4] (MASLD), retatrutide achieved reductions in relative hepatic fat content of 8082%
Despite these positive findings, other studies have reported cases of acute kidney injury in patients using semaglutide
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The medication mimics the hormone GLP-1, which regulates appetite and food intake which can help lead to reduced hunger and subsequently, calorie consumption
Resultant oxidative DNA base lesions have the potential to mutate some genetic material, which would impair the integrity of the genome by preventing transcription and replication and by generating mutagenesis (116)
However, as discussed by Barbarich-Marsteller et al