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Prior to newborn screening, up to 21% (60) of cases of autism were later found to have biochemical evidence of untreated PKU, and in a recent study, about 5.7% of untreated patients were diagnosed with ASD (61)

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Reviewed and updated January 2010 IMPORTANT REMINDER: This information is intended only to provide general guidance

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In addition, previous studies have shown that LRP1 can be combined with tissue plasminogen activator (t-PA) to promote HSC apoptosis and reverse HSC activation [41]